Matt Johnson, the creator of Dewclaw writes a bit at PV Comics about how he came to use Flash for his webcomic and how he has evolved his approach to the art while remaining true to the story he wanted to tell.

For me, Dewclaw is a great webcomic. The fact that it is in Flash (and sometimes makes use of Flash's animation capabilities) is never the first thing that comes to mind to me when I think about why I like Dewclaw.