Maritza Campos has been making College Roomies From Hell!!! since 1999. She's progressed considerably in her approach to both the artwork and the stories driving CRFH!!! Here's one of the very first ones and one from earlier this year.
One of the things that is interesting about webcomics is the very public nature of an artist's development. Case in point: Jeph Jacques and Questionable Content. Compare the very first one with a very recent comic.