We used to do an irregularly recurring bit here at ComixTALK called "First and Last" which seemed like a good idea to revive. Particularly with a comic like Anders Loves Maria where creator Rene Engström has not only constantly improved but also taken several stylistic leaps during the comic.
Here's a snippet from the first comic was posted in 2006:
I'm not going to post the very last comic (trying not to create a spoiler here) but this is close enough:
There were many times Engström mixed up her approach — I thought the series with washed colors was very good: