Along with APE and MoCHA, I think SPXPo is the most webcomic-friendly venue going. The vibe at SPXPo is artist-friendly and a lot of attention is paid to non-superhero comic book type works. (I’m not even sure if I’ve ever seen a Marvel or DC type at SPXPo).
Webcomic creators might consider crafting a print version for the SPX Anthology as the SPXPo crowd is probably a good audience to get your work in front of. Submissions for the anthology must be received no later than June 30, 2005.